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Amikacin-250mg Inj
A high-potency aminoglycoside antibiotic injection formulated for the management of moderate to severe systemic bacterial infections. ZAMI-250 contains Amikacin 250mg, providing a broad-spectrum bactericidal effect against multi-drug resistant Gram-negative pathogens.
A high-potency aminoglycoside antibiotic injection formulated for the management of moderate to severe systemic bacterial infections. ZAMI-250 contains Amikacin 250mg, providing a broad-spectrum bactericidal effect against multi-drug resistant Gram-negative pathogens.
Amikacin 250mg acts by irreversibly binding to the 30S ribosomal subunit of the bacteria. This disrupts the translation of mRNA, leading to the synthesis of non-functional proteins and the eventual death of the bacterial cell.
Amikacin is structurally designed to be less susceptible to the enzymes that often deactivate other aminoglycosides. This makes it a critical therapeutic option for treating infections caused by bacteria resistant to Gentamicin or Kanamycin.
The formulation is highly effective against a wide range of aerobic Gram-negative organisms, including Pseudomonas aeruginosa, Proteus species, and Serratia marcescens, which are frequently associated with hospital-acquired infections.
The injectable delivery ensures that therapeutic drug levels are achieved quickly in the bloodstream. It offers excellent penetration into vital tissues, including the respiratory tract and the renal system, for the effective management of acute conditions.
The 250mg dosage strength provides a versatile option for both pediatric and adult patients, allowing for precise weight-based dosing to ensure maximum efficacy while monitoring for safety.
When used in combination with other classes of antibiotics, such as penicillins or cephalosporins, Amikacin provides a synergistic effect that expands the spectrum of activity, particularly in critically ill or immunocompromised patients.
Indication Septicemia (Bloodstream Infections), Complicated Urinary Tract Infections, Severe Lower Respiratory Tract Infections, Skin and Soft Tissue Infections, Intra-abdominal Infections, Meningitis and Central Nervous System Infections.
Product descriptions, dosage forms, and compositions listed on the website are for reference by licensed practitioners and distributors only.
